Indiana Pacers vs Cleveland Cavaliers Final Score & Over/Under Result — Nov 21, 2025

The opening quarter set a frenetic pace, with Cleveland and Indiana combining for 64 points—the game's highest-scoring frame. But it was the third quarter that ultimately decided this matchup. After a relatively subdued second half began with 53 combined points in Q2, the two teams exploded again for 64 in the third, allowing Cleveland to build a cushion the Pacers could never quite close. Indiana's fourth-quarter rally, which produced 28 points, came too late; Cleveland's 20-point fourth pushed the Cavaliers to a 120–109 victory with a combined final total of 229.

Andrew Nembhard led the Pacers with 32 points and 8 assists, while Pascal Siakam added 26 points and 9 rebounds and Bennedict Mathurin chipped in 21 points. For Cleveland, Donovan Mitchell matched Nembhard with 32 points and 9 rebounds to go with 5 assists, and Evan Mobley contributed a game-high 12 rebounds alongside 22 points. De'Andre Hunter rounded out the Cavaliers' scoring with 20 points.

The 1st half saw 117 combined points while the 2nd half settled into 112, reflecting a slight defensive tightening late. Cleveland's recent form—averaging 123.6 points scored per game over its last 10—held steady here, while Indiana's defensive vulnerabilities (yielding 122.8 per game) proved decisive in the home loss.